Separated at Birth SPECIAL EDITION -- Jerry Maguire and Love and Other Drugs

Successful-in-the-bedroom-but-not-in-the-boardroom protagonists: Tom Cruise (sports agent) and Jake Gyllenhaal (pharmaceutical sales)



Women who complete them despite their significant baggage: Renee Zellweger (kid) and Anne Hathaway (Parkinsons)



Spark plug superstars who help their agent advance their career: Cuba Gooding Jr. (Wide Receiver) and Viagra (boioioioioing)



Four eyed comic relief: Jonathan Lipnicki (kid) and Josh Gad (Jonah Hill clone)